It's really interesting how rapidly Ruger is introducing new firearms these days! You have no shortage of options, to be sure.
I really liked the "ergonomics" and shootability of the Ruger SR series when someone here let me shoot his. (I think it was Gumby, or Gumby's son.) The design really allows you to grip way up high. One of the better pistol designs I've ever fired in terms of being able to put a lot of shots on a target very fast.
When Ruger introduced the economy version, the 9E (which eliminated the loaded chamber indicator) I was all over it. Got one for $295, shipping included. They regularly go for around $300. Really hard to beat that.
Now they introduce the American Pistol which eliminates a couple more things compared to the 9E: it has no thumb safety, and no magazine disconnect. More along the lines of their "pro series" LC9s. A Glock competitor. For people who carry a pistol for risk-prone work like police and armed security (or to put Ruger in the running for government contracts) this sure seems to complete their lineup. Pretty soon you'll probably seen a compact version of it, I reckon. It looks like it shares the SR / 9e ergonomics.
I do hope they retain the SR / 9e pistols. For a family-fun range gun, I think the safety and mag disconnect aren't all bad.