Most of the time, for its lightness and concealability, I carry my S&W 340SC. I have a good ankle holster for it (De Santis 044 S1), but I prefer a pocket or my Galco paddle holster if I can wear a long shirt or jacket for cover. It will fit just about anywhere, even a jeans pocket, and printing isn't usually a problem. It's not something I enjoy shooting (quite a kick with .357 Mag 140 gr FTX Hornady Leverevolution ammo), but it has stopping power if not capacity. I figure the most likely situation where I might need it would be at very close range and a single attacker.
I really prefer to carry my Kimber .45 with night sights, but its not as comfortable or concealable. I usually use my Galco B819WC belt holster (for concealed or open carry), but if I expect to have to remove it for some reason, I will use my Galco paddle hoster instead. I don't usually use it, but I have a two-magazine carrier that matches my paddle holster, too. I frequently open carry if I'm taking my dogs for a walk, or just going for a walk on my own. That doesn't go over very well though if I'm going to a place with lots of people around (shopping, etc.).
I generally have my Glock 26 in my truck in the overhead console as well.