Ever since I got my CCP last year, I've carried with one in the chamber. Initially I was concerned about where the muzzle was pointed (since I often pocket carry), but I've learned to be comfortable with passive safeties of my gun (no thumb safety, but things like the trigger safety on my LC9s Pro and the striker bar on that and my P2000). Is there still a chance of AD? Yes, but I've learned not to let it constantly bother me (I still consider it, I just don't obsess over it).